EMILIN1 inhibits tumor growth and lymphatic spread

نویسندگان

  • Carla Danussi
  • Alessandra Petrucco
  • Bruna Wassermann
  • Teresa Maria Elisa Modica
  • Eliana Pivetta
  • Lisa Del Bel Belluz
  • Alfonso Colombatti
  • Paola Spessotto
  • Franco Gallini
چکیده

Running title: EMILIN1 inhibits tumor growth and lymphatic spread Conflict of interest: No conflict of interest has to be disclosed. Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. EMILIN1 inhibits tumor growth and lymphatic spread 2 ABSTRACT The evidence that EMILIN1 deficiency in Emilin1-/-mice caused dermal and epidermal hyperproliferation and an abnormal lymphatic phenotype prompted us to hypothesize the involvement of this extracellular matrix component in tumor development and in lymphatic metastasis. Using the

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تاریخ انتشار 2012